Staff Directory

About Martin Lear

Prof Dr Martin Lear is a Reader (Assoc. Prof.) in the School of Chemistry, College of Science, and is an Adjunct Professor of the Global Leader Program at Tohoku University, Science and Engineering. He has spent over 18 years in Asia (mostly in Japan at Tohoku University, with 8 years tenure at the National University of Singapore) and has co-founded a drug-labelling company to combat drug resistance. To date, he has enjoyed mentoring and learning research from 17 PhD, 5 MSc, and 36 BSc students. His current interests lie in developing transition metal-free oxidative methods and applying these methods in both an organic synthesis and MedChem context.

Department Responsibilities

(Bio)Organic chemistry teaching (AY2015, to-date) Level-2 programme tutor (AY2015, AY2016) Level-3 programme tutor (AY2017, to-date) Exam committee member (AY2016, to-date)

Subject Specialism

Targeted synthesis & new oxidative methods (transition metal-free)

Qualifications

  • PhD - Synthesis & Biological Evaluation of Anticancer Agents — The University of Glasgow, 1996
  • BSc - Honours (Special) in Chemistry with Computer Applications (MedChem) — The University of Glasgow, 1991

Awards

  • Associate College Member of EPSRC — EPSRC Associate Peer Review College, UK,
  • Fellow of HEA — The Higher Education Academy, UK,
  • ACP Lectureship Award — Asian Core Program on Cutting Edge Organic Chemistry,
  • CREST Research Fellow — Ministry of Education, Culture, Sports, Science & Technology,
  • JSPS Research Fellow — Japanese Society for the Promotion of Science,
  • Fellow of Wolfson College — The University of Cambridge,
  • CChem, MRSC — The Royal Society of Chemistry,
  • PhD Scholarship — The Senate of the University of Glasgow,

Orcid ID

0000-0003-2556-2029

Research Interests

  • Asymmetric halogenation

  • Bioimaging

  • Chemical Libraries

  • Halogen bonding

  • Lead discovery

  • Mode-of-action

  • Natural Products

  • Organic synthesis

  • Oxidative functionalisations

  • Photo-redox methods

  • Photo-smart probes

  • Total synthesis

Research Projects

  • One-pot, oxidative methods to form activated esters from atypical substrates under transition metal-free conditions — University of Lincoln; started in 2017
  • Translating Malaria Cell Death into Novel Anti-Malarial Strategies (over 3 years) — awarded £415000 by NMRC/IRG11may097 of Singapore; ended in 2015
  • Fluorescent Tagged Antimalarials as Commercial Molecular Probes to Diagnose Drug Resistance and to Study Diseases (over 1 + 2 years) — awarded £330000 by Singapore proof-of-concept (POC) and proof-of-value (POV) company start-up grants; ended in 2014
  • Lipidomics, novel tools and applications (over 5-years) — awarded £4987000 by NRF-G-CRP 2007-04 of Singapore as part of a consortium; ended in 2013
  • Synthesis and biology of future anti-malarials derived from bielschowskysin (over 3-years) — awarded £315000 by AcRF-MoE Tier-II (T206B1112) of Singapore; ended in 2010
  • Organic Synthesis - various start-up grants (over 4 years) — awarded £160000 by National University of Singapore, Bioimaging Consortium and BMRC of Singapore; ended in 2008
  • Total synthesis of the kedarcidin chromophore (over 2 years) — awarded £12400 by Grant in Aid of Scientific Research, Wakate B, MEXT A of Japan; ended in 2004

Research in the Lincoln Repository


Professional Affiliations