Staff Directory

About Paul Squires

Professor in Biomedical Science (Diabetes & Endocrinology) PhD, BSc, FPhysiol My research into diabetes mellitus, aims to better understand the sub-cellular mechanisms that regulate insulin secretion and action in health and disease. A common theme linking our work is determining how cell-cell adhesion, cell-coupling and cell-to-cell communication synchronise activity and function within the renal nephron and pancreatic islet. For more details see: RESEARCH CAREER 2014-present Professor of Biomedical Science (Diabetes), University of Lincoln, UK 2010-2014 Reader in Diabetes & Endocrinology, University of Warwick, UK 2005-2010 Senior Lecturer in Molecular Physiology, University of Warwick, UK 2001-2004 Honorary Lecturer, King’s College London, UK 2001-2005 Lecturer in Cellular Signalling, University of Warwick, UK 1997-2001 Diabetes UK, RD Lawrence Research Fellow, King’s College London, UK 1998 EASD/Bayer & Peter Baker Traveling Research Fellow, Uppsala, Sweden 1996-1997 Izaak Walton Killam Research Fellow, University of British Columbia, Vancouver, Canada 1995-1996 Royal Society Traveling Research Fellow, University of British Columbia, Vancouver, Canada 1992-1995 Wellcome Trust Research Fellow, University of Sheffield, UK

Department Responsibilities

Member of the Lincoln Institute for Health (LIH) Advisory Group Member of the School Research Committee Member of the School Management Committee Member of the Health & Safety Committee Chair of School Pump-priming Scheme Joint Lead for the Master in Biosciences (MBio) programmes Module Lead for MBio Research Projects

Subject Specialism

Diabetes & Endocrinology


  • Certificate in Post-Compulsory Higher Education — University of Warwick, 2003
  • PhD — University of Sheffield, 1992
  • BSc Physiology — University of Sheffield, 1988


RESEARCH ADVISORY BOARD MEMBERSHIP: 2005-2013 Diabetes UK (DUK) Main panel. 2010-2016 Diabetes Research & Wellness Foundation (DRWF). 2013 Diabetes UK (DUK) RD Lawrence Fellowship panel 2012, 2014 European Foundation for the Study of Diabetes (EFSD). 2015 Diabetes UK (DUK) Studentship Panel. 2016-present European Diabetes Wellness Network (Sweden). MEMBERSHIP OF LEARNED SOCIETIES: Fellow of the Physiological Society (London) Member of the European Association for the Study of Diabetes (EASD) Member of Diabetes UK (DUK) Member of the British Society for Endocrinology (BES) RESEARCH RELATED ACTIVITIES: External Examiner (2006-2010): MSc Program in Biomedicine & Molecular Science Research, KCL External Assessor (2012) Periodic Review, Peninsula College of Medicine & Dentistry’s Grad School. External Assessor (2013) Periodic Review, Biomedical Science, University of Ulster, Coleraine, NI. External Examiner (2015-2018): BSc Program in Biomedical Science, University of Ulster. External Assessor (2017) Periodic Review, Biomedical & Healthcare Science, MMU, Manchester.

Orcid ID


Research Interests

  • Cell-to-cell communication

  • Diabetes

  • Diabetic nephropathy

  • Islet structure-function

Research Groups Memberships

Research Projects

  • EFSD/Boehringer Ingelheim Research Programme in Microvascular Complications of Diabetes — EFSD in 2017
  • Understanding how remodeling of the ECM and altered cell-substrate interactions facilitate progression of tubulointerstitial fibrosis — Diabetes UK in 2017
  • Determining a role for connexin mediated cell communication in the progression of renal fibrosis in the diabetic kidney — Diabetes UK in 2016
  • Understanding the bioscience of cell-adhesion and membrane dynamics that underpin health — Nigerian Petroleum Technology Development Fund in 2015
  • Developing the Lincolnshire joint research agenda for chronic health conditions (Co-I) — Research Investment Fund in 2015
  • The role of the extracellular matrix and cell-substrate interactions in human proximal tubule cells — EFSD/Janssen Kidney Award in 2015
  • Does reorganization of the ECM promote a loss of phenotypic stability in diabetic nephropathy? — WPH Charitable Trust in 2014
  • Cyclosporin A and fibrosis: implications for graft survival. — RDF University of Warwick in 2013
  • Special K and urological complications of ketamine abuse. — The Rosetree Trust in 2013
  • AFM single-cell force spectroscopy: determining the functional role of cell-cell adhesion and membrane dynamics in diabetes. — Diabetes UK in 2012
  • The importance of cell-to-cell contact in diabetic nephropathy: identifying potential novel targets for therapeutic intervention. — WPH Charitable Trust in 2012
  • The effect of TGF-beta on cell-adhesion, cell coupling and cell communication in the kidney. — EFSD/Janssen Kidney Award in 2011
  • The effect of TGF-beta on connexin-mediated signalling: a role in diabetic nephropathy. — Diabetes UK in 2011

Research in the Lincoln Repository

Professional Affiliations