Staff Directory

About Neil Holden

Senior Lecturer in Life Sciences in the College of Science My major research interests revolve around the interaction between anti-inflammatory and pro-inflammatory pathways in inflammatory airway diseases predominantly Asthma and chronic obstructive pulmonary disease (COPD). Corticosteroids (aka glucocorticoids) are the mainstay therapy of the inflammatory lung diseases asthma and COPD. In more severe cases of these diseases they are often taken in combination with “reliever” therapies, such as long acting Beta 2 adrenergic receptor agonists (LABA’s), as these combinations have been shown to be more beneficial than corticosteroids alone. However it is not entirely clear the anti-inflammatory molecular mechanisms these drugs activate within the various lung cells. I have previously developed a strong interest in proteins who have potential anti-inflammatory activities and whose expression is driven by corticosteroids and/or LABAs.  My current research projects are focused on the interaction of these anti-inflammatory proteins with respiratory viruses, which are the leading causes of exacerbations and therefore morbidity and mortality in asthma and COPD. 

Department Responsibilities

Lecturers in various Modules on Virology, Immunology, Respiratory Pharmacology, and Airway Diseases Module leader for Medical and Veterinary Microbiology Module leader for Fundamentals of Pharmacology and Toxicology Module leader for Molecular Virology (MSc Microbiology)

Subject Specialism

Airway Inflammatory Diseases, Asthma & COPD, Virology and Immunology


  • PhD in Molecular Physiology — The University of Warwick, 2006
  • BSc in Virology with Intercalated Year — The University of Warwick, 2001


  • Eric Reid Fund for Methodology — Biochemical Society,
  • Izaac Walton Killam Postdoctoral Fellowship — Killam Trusts,

Orcid ID


Research Interests

  • Asthma

  • beta 2 adrenoceptor agonists

  • COPD

  • Corticosteroids

  • Inflammation

  • Respiratory Syncytial Virus

  • Viruses

Research Groups Memberships

  • Diabetes, Metabolism and Inflammation

Research in the Lincoln Repository

Professional Affiliations